Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, Aviva Breuer, Roger G. Pertwee et al. · Science · 1992 · 5.6K citations

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Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt Rd, Aurélie Bertin, M Jalfre · PubMed · 1977 · 3.3K citations

Medicine, Pharmacology, Psychiatry +17

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

Raphael Mechoulam, Shimon Ben‐Shabat, L Hanŭs et al. · Biochemical Pharmacology · 1995 · 2.9K citations

Life Sciences, Pharmacology, Veterinary Pharmacology +10

Cannabinoid receptor localization in brain.

Miles Herkenham, A B Lynn, M.D. Little et al. · Proceedings of the National Academy of Sciences · 1990 · 2.3K citations

Life Sciences, Neuroscience, Pharmacology +13

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

Miles Herkenham, A B Lynn, MR Johnson et al. · Journal of Neuroscience · 1991 · 2.2K citations · Full text

Medicine, Neuroscience, Pharmacology +14