Materials science forum · 2005 · 14 citations · 5 references
EngineeringBioengineeringMaterials ScienceBiocompatibilityBiomaterialsTissue EngineeringBiomaterials For Tissue EngineeringCell-scaffold InteractionsRegenerative ScaffoldsScaffold DesignScaffold FabricationTissue Engineering ScaffoldsBiodegradable ScaffoldsBiomaterial ScaffoldsComposite ScaffoldsElectrospinningPolymer ScaffoldsPolymer-based ScaffoldsScaffold CharacterizationTissue Engineering Scaffold Fabrication
In recent years, electrospinning process is gradually applied in producing tissue-engineering scaffold. In this study, we chose polylacticacid(PLA) and β-tertiary calcium phosphate(β-TCP) as raw materials to fabricate PLA/β-TCP biodegradable composite scaffold by electrospinning process. The characteristics of the scaffold and effect of the scaffolds to cell proliferation and cell adhesion was studied. Compare with pure PLA scaffold, blendingβ-TCP in the spinning process of the scaffold could improve the properties of the scaffold, especially the hydrophilicity and the proliferation and adhesion of cells, this means that the material is more potential to be used as tissue engineering scaffolds.
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