Outcomes of Childhood Pulmonary Arterial Hypertension in BMPR2 and ALK1 Mutation Carriers

Survival in Patients with Primary Pulmonary Hypertension

Gilbert E. D’Alonzo, Robyn J. Barst, Stephen M. Ayres et al. · Annals of Internal Medicine · 1991 · 3.5K citations

Medicine, Cardiology, Pulmonary Function Testing +12

Primary Pulmonary Hypertension

Stuart Rich · Annals of Internal Medicine · 1987 · 2.1K citations

Medicine, Cardiology, Internal Medicine +12

Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension

Kirk B. Lane, Rajiv D. Machado, Michael W. Pauciulo et al. · Nature Genetics · 2000 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +12

Familial Primary Pulmonary Hypertension (Gene PPH1) Is Caused by Mutations in the Bone Morphogenetic Protein Receptor–II Gene

Zemin Deng, Jane H. Morse, Susan L. Slager et al. · The American Journal of Human Genetics · 2000 · 1.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +7

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-β family

Jennifer R. Thomson · Journal of Medical Genetics · 2000 · 734 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15