Kirk B. Lane

Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension

Kirk B. Lane, Rajiv D. Machado, Michael W. Pauciulo et al. · Nature Genetics · 2000 · 1.5K citations

Hypertension, Pulmonary Arterial Hypertension, Tgf-β Receptor +11

Heterozygosity for a Surfactant Protein C Gene Mutation Associated with Usual Interstitial Pneumonitis and Cellular Nonspecific Interstitial Pneumonitis in One Kindred

Alan Q. Thomas, Kirk B. Lane, John A. Phillips et al. · American Journal of Respiratory and Critical Care Medicine · 2002 · 644 citations

BMPR2 Haploinsufficiency as the Inherited Molecular Mechanism for Primary Pulmonary Hypertension

Rajiv D. Machado, Michael W. Pauciulo, Jennifer R. Thomson et al. · The American Journal of Human Genetics · 2001 · 533 citations · Full text

Hypertension, Pulmonary Arterial Hypertension, Pulmonary Circulation +12

Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection

William E. Lawson, Peter F. Crossno, Vasiliy V. Polosukhin et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2008 · 439 citations

Immunology, Viral Pathogenesis, Pulmonary Alveolar Proteinosis +19

Mutation in the Gene for Bone Morphogenetic Protein Receptor II as a Cause of Primary Pulmonary Hypertension in a Large Kindred

John H. Newman, Lisa Wheeler, Kirk B. Lane et al. · New England Journal of Medicine · 2001 · 367 citations · Full text