Kirk B. Lane

Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension

Kirk B. Lane, Rajiv D. Machado, Michael W. Pauciulo et al. · Nature Genetics · 2000 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +12

Heterozygosity for a Surfactant Protein C Gene Mutation Associated with Usual Interstitial Pneumonitis and Cellular Nonspecific Interstitial Pneumonitis in One Kindred

Alan Q. Thomas, Kirk B. Lane, Melissa Prince et al. · American Journal of Respiratory and Critical Care Medicine · 2002 · 645 citations

Life Sciences, Genetics, Molecular Genetics +14

BMPR2 Haploinsufficiency as the Inherited Molecular Mechanism for Primary Pulmonary Hypertension

Rajiv D. Machado, Michael W. Pauciulo, Jennifer R. Thomson et al. · The American Journal of Human Genetics · 2001 · 537 citations · Full text

Medicine, Genetics, Molecular Genetics +14

Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection

William E. Lawson, Peter F. Crossno, Vasiliy V. Polosukhin et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2008 · 441 citations

Veterinary Medicine, Cell Biology, Pathobiology +17

Mutation in the Gene for Bone Morphogenetic Protein Receptor II as a Cause of Primary Pulmonary Hypertension in a Large Kindred

John H. Newman, Lisa Wheeler, Kirk B. Lane et al. · New England Journal of Medicine · 2001 · 369 citations · Full text

Medicine, Genetics, Molecular Genetics +11