Concepedia

Down-Regulation of miR-126 Is Associated with Colorectal Cancer Cells Proliferation, Migration and Invasion by Targeting IRS-1 via the AKT and ERK1/2 Signaling Pathways

Yu Zhou, Xiao Feng, Yaling Liu, Shicai Ye, Hao Wang, Wenkai Tan, Ting Tian, Yumei Qiu, Hesheng Luo

PLoS ONE · 2013 · 77 citations · 36 references

Open access

Abstract

MiR-126 may play roles in regulation of the biological behavior of CRC cells, at least in part, by targeting IRS-1 via AKT and ERK1/2 signaling pathways.

References

36

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Ahmedin Jemal, Freddie Bray · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

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Donald Maxwell Parkin, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2005 · 18.4K citations · Full text

Epidemiology Of Cancer, Worldwide Incidence, Cancer Registration +16

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Jun Lü, Gad Getz, Eric A. Miska et al. · Nature · 2005 · 9.5K citations

Pathology, Cancer Genomics, Microrna Expression Profiles +6

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

Philip A. Gregory, Andrew G. Bert, Emily Paterson et al. · Nature Cell Biology · 2008 · 3.8K citations

Mir-205 Regulate Epithelial, Epithelial-mesenchymal Transition, Developmental Biology +9

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

Sun-Mi Park, Arti Gaur, Ernst Lengyel et al. · Genes & Development · 2008 · 2.3K citations · Full text