Concepedia

The role of reductive and oxidative metabolism in the toxicity of mitoxantrone, adriamycin and menadione in human liver derived Hep G2 hepatoma cells

MH Grant

British Journal of Cancer · 1989 · 49 citations · 31 references

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Concepts

References

31

A fluorometric method for determination of oxidized and reduced glutathione in tissues

Paul J. Hissin, Russell Hilf · Analytical Biochemistry · 1976 · 4.1K citations

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The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

Hjördis Thor, Martyn T. Smith, Pia Hartzell et al. · Journal of Biological Chemistry · 1982 · 903 citations · Full text

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DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

Christina Lind, Paul Hochstein, Lars Ernster · Archives of Biochemistry and Biophysics · 1982 · 531 citations

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Mutagenicity of quinones: pathways of metabolic activation and detoxification.

Paul L. Chesis, David E. Levin, Martyn T. Smith et al. · Proceedings of the National Academy of Sciences · 1984 · 389 citations

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Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

Donato A. Di Monte, Giorgio Bellomo, Hjördis Thor et al. · Archives of Biochemistry and Biophysics · 1984 · 375 citations

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