Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. II. ROLE OF COVALENT BINDING IN VIVO

David J. Jollow, John R. Mitchell, William Z. Potter et al. · Journal of Pharmacology and Experimental Therapeutics · 1973 · 1.2K citations

Veterinary Medicine, Pharmacology, Toxicology +17

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

Hjördis Thor, Martyn T. Smith, Pia Hartzell et al. · Journal of Biological Chemistry · 1982 · 903 citations · Full text

Life Sciences, Biochemistry, Toxicology +16

A scheme for the colorimetric determination of microgram amounts of thiols

B. Saville · The Analyst · 1958 · 750 citations

Natural Sciences, Biochemistry, Analytical Chemistry +7

Intracellular production of superoxide radical and of hydrogen peroxide by redox active compounds

Hosni M. Hassan, Irwin Fridovich · Archives of Biochemistry and Biophysics · 1979 · 598 citations

Life Sciences, Biochemistry, Cell Biology +16

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

Sarah A. Jewell, Giorgio Bellomo, Hjördis Thor et al. · Science · 1982 · 555 citations

Life Sciences, Biochemistry, Cell Biology +16