CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

G J Zaman, M J Flens, Manuel R. van Leusden et al. · Proceedings of the National Academy of Sciences · 1994 · 692 citations · Full text

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Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.

John M. Zamora, Homer L. Pearce, William T. Beck · Molecular Pharmacology · 1988 · 414 citations

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Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors.

Takehiko Kunimoto, Kazuo Nitta, Takashi Tanaka et al. · PubMed · 1987 · 412 citations

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Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

Alfred M. Rogan, Thomas C. Hamilton, Robert C. Young et al. · Science · 1984 · 399 citations

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