Efficient Hypoxic Activation of the Anticancer Agent AQ4N by CYP2S1 and CYP2W1

Cytochrome P450 Profile of Colorectal Cancer: Identification of Markers of Prognosis

Meera Kumarakulasingham, Patrick H. Rooney, Sinclair R. Dundas et al. · Clinical Cancer Research · 2005 · 170 citations

Medicine, Oncology, Pharmacology +16

Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer

Phyu P. Aung, Naohide Oue, Yoshitsugu Mitani et al. · Oncogene · 2005 · 164 citations · Full text

Medicine, Cancer Biology, Oncology +14

Profiling Cytochrome <i>P</i>450 Expression in Ovarian Cancer: Identification of Prognostic Markers

Diane L. Downie, Morag McFadyen, Patrick H. Rooney et al. · Clinical Cancer Research · 2005 · 164 citations

Medicine, Oncology, Pharmacology +16

Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases

Gillian Smith, C. Roland Wolf, Yusuf Deeni et al. · The Lancet · 2003 · 145 citations

Medicine, Dermatology, Pharmacology +13

Hypoxia-Selective Targeting by the Bioreductive Prodrug AQ4N in Patients with Solid Tumors: Results of a Phase I Study

Mark R. Albertella, Paul M. Loadman, Philip H. Jones et al. · Clinical Cancer Research · 2008 · 127 citations

Medicine, Oncology, Pharmacology +15