Profiling Cytochrome <i>P</i>450 Expression in Ovarian Cancer: Identification of Prognostic Markers

Abstract

The expression profile of individual P450s has been established in ovarian cancer. Several P450s show increased expression in ovarian cancer and this provides the basis for developing P450-based therapeutics in ovarian cancer. Expression of CYP2A/2B or CYP4Z1 in primary ovarian cancer were independent markers of prognosis.