Concepedia

The Artemisinin Derivative Artesunate Inhibits Corneal Neovascularization by Inducing ROS-Dependent Apoptosis in Vascular Endothelial Cells

Rui Cheng, Cen Li, Chaoyang Li, Ling Wei, Lei Li, Yang Zhang, Yachao Yao, Xiaoqiong Gu, Weibin Cai, Zhonghan Yang,

Investigative Ophthalmology & Visual Science · 2013 · 54 citations · 22 references

DOIFull text

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Abstract

These results suggest that artesunate induces apoptosis of endothelial cells via an iron/ROS-dependent p38MAPK-mitochondrial pathway.

References

22

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, , +9

Risk Factors for Various Causes of Failure in Initial Corneal Grafts

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Amy E. Mercer, James L. Maggs, Xiaoming Sun et al. · Journal of Biological Chemistry · 2007 · 191 citations · Full text

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Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin

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, , +4

Artesunate in the treatment of metastatic uveal melanoma - first experiences

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