Concepedia

GSK3β negatively regulates HIF1α mRNA stability via nucleolin in the MG63 osteosarcoma cell line

Dongdong Cheng, Haiguang Zhao, Yun‐Song Yang, Tu Hu, Qingcheng Yang

Biochemical and Biophysical Research Communications · 2013 · 27 citations · 26 references

DOI

Concepts

References

26

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

, , +17

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text

, , +16

Hypoxia-inducible Factor 1α (HIF-1α) Protein Is Rapidly Degraded by the Ubiquitin-Proteasome System under Normoxic Conditions

Susana Alicia Salceda, J. Jaime · Journal of Biological Chemistry · 1997 · 1.7K citations · Full text

, , +15

Molecular cloning and expression of glycogen synthase kinase‐3/factor A.

James R. Woodgett · The EMBO Journal · 1990 · 1.4K citations · Full text

, , +11

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1

Dominador J. Manalo, Ashley Rowan, Tera Lavoie et al. · Blood · 2004 · 1.2K citations

, , +14