Targeting Double-Strand Breaks to Replicating DNA Identifies a Subpathway of DSB Repair That Is Defective in Ataxia-Telangiectasia Cells

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

Kinneret Savitsky, Anat Bar‐Shira, Shlomit Gilad et al. · Science · 1995 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +11

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin.

Y H Hsiang, M G Lihou, Leroy F. Liu · PubMed · 1989 · 1K citations

Life Sciences, Cell Biology, Molecular Biology +17

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

A. Malcolm R. Taylor, D.G. Harnden, C.F. Arlett et al. · Nature · 1975 · 989 citations

Life Sciences, Genetics, Molecular Genetics +16

Radiosensitivity in ataxia-telangiectasia: a new explanation.

Robert B. Painter, B.R. Young · Proceedings of the National Academy of Sciences · 1980 · 789 citations · Full text

Medicine, Cancer Biology, Oncology +17

Differential induction of transcriptionally active p53 following UV or lonizing radiation: Defects in chromosome instability syndromes?

Xin Lü · Cell · 1993 · 783 citations · Full text

Life Sciences, Genetics, Molecular Biology +16