Shoshana Squires

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

Jim McWhir, Jim Selfridge, David J. Harrison et al. · Nature Genetics · 1993 · 320 citations

Knockout Mouse, Dna Repair Gene, Genome Instability +9

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA

Anderson J. Ryan, Shoshana Squires, Helen Strutt et al. · Nucleic Acids Research · 1991 · 227 citations · Full text

Genome Instability, Dna Damage, Camptothecin Cytotoxicity +15

Cells from <i>ercc1</i>-deficient mice show increased genome instability and a reduced frequency of s-phase-dependent illegitimate chromosome exchange but a normal frequency of homologous recombination

David W. Melton, Ann-Marie Ketchen, F. Rueda Núñez et al. · Journal of Cell Science · 1998 · 95 citations

Genetics, Cell Proliferation, Cell Cycle +17

Initial rates of DNA incision in UV-irradiated human cells differences between normal, xeroderma pigmentosum and tumour cells

Shoshana Squires, Robert T. Johnson, Andrew Collins · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1982 · 89 citations

Chromatin, Xeroderma Pigmentosum, Dna Damage +12

Inhibitors of repair DNA synthesis

Andrew Collins, Shoshana Squires, Robert T. Johnson · Nucleic Acids Research · 1982 · 80 citations · Full text