Synthetic peptide purification by application of linear solvent strength gradient theory

<b>Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide</b>

R. B. Merrifield · Journal of the American Chemical Society · 1963 · 7.6K citations

Natural Sciences, Biochemistry, Chemistry +6

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

Richard A. Houghten · Proceedings of the National Academy of Sciences · 1985 · 1.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Gradient elution in high-performance liquid chromatography

Lloyd R. Snyder, John W. Dolan, J.R. Gant · Journal of Chromatography A · 1979 · 841 citations

Pharmacy, Chemistry, Analytical Chemistry +12

Prediction of peptide retention times in reversed-phase high-performance liquid chromatography I. Determination of retention coefficients of amino acid residues of model synthetic peptides

Dacheng Guo, Colin T. Mant, Ashok K. Taneja et al. · Journal of Chromatography A · 1986 · 306 citations

Pharmacy, Biochemistry, Chromatographic Analysis +13

Gradient elution in high-performance liquid chromatography

John W. Dolan, J.R. Gant, Lloyd R. Snyder · Journal of Chromatography A · 1979 · 221 citations

Pharmacy, Chemistry, Analytical Chemistry +12