Human β-thromboglobulin inhibits PGI2 production and binds to a specific site in bovine aortic endothelial cells

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Statistical Quality Control and Routine Data Processing for Radioimmunoassays and Immunoradiometric Assays

David Rodbard · Clinical Chemistry · 1974 · 1K citations · Full text

Public Health, Biostatistics, Immunology +12

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

Ryszard J. Gryglewski, Stuart Bunting, Salvador Moncada et al. · Prostaglandins · 1976 · 1K citations

Medicine, Cardiology, Hematology +13

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

Stuart Bunting, Salvador Moncada, John R. Vane et al. · Prostaglandins · 1976 · 955 citations

Medicine, Physiology, Signal Transduction +11

HUMAN VASCULAR ENDOTHELIAL CELLS IN CULTURE

Michael A. Gimbrone, Ramzi S. Cotran, Judah Folkman · The Journal of Cell Biology · 1974 · 835 citations · Full text

Life Sciences, Cell Biology, Cell Physiology +8