Concepedia
Behavioural Brain Research · 2001 · 136 citations · 24 references
Life SciencesGeneticsNeurologyNeurobiology Of DiseaseNeurodegenerationNeurogeneticsDiabetes MellitusGenetic DisordersHuntington DiseaseNeurodegenerative DiseasesNeurodegenerative DisordersRodent GeneticsHuntington Disease Gene TherapyHuntington's Disease ModelsTransgenic Mice
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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text
Life Sciences, Genetics, Molecular Genetics +13
Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice
Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text
Life Sciences, Genetics, Molecular Genetics +17
Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation
Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text
Life Sciences, Genetics, Neurology +17
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
Minghua Chen, Victor Ona, Mingwei Li et al. · Nature Medicine · 2000 · 1.1K citations
Life Sciences, Neurology, Neuroscience +17
Characterization of Progressive Motor Deficits in Mice Transgenic for the Human Huntington’s Disease Mutation
Rebecca J. Carter, Lisa A. Lione, Trevor Humby et al. · Journal of Neuroscience · 1999 · 959 citations · Full text