Concepedia

Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection

Brianne Kallam, James Arthos, Claudia Cicala, Fatima Nawaz, Joseph Hiatt, Ellen N. Kersh, Janet M. McNicholl, Debra L. Hanson, Keith A. Reimann, Markus Brameier,

Nature Medicine · 2014 · 140 citations · 28 references

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28

Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis

Brian G. Feagan, Paul Rutgeerts, Bruce E. Sands et al. · New England Journal of Medicine · 2013 · 2.9K citations · Full text

, , +15

Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease

William J. Sandborn, Brian G. Feagan, Paul Rutgeerts et al. · New England Journal of Medicine · 2013 · 2.7K citations · Full text

, , +14

Gastrointestinal Tract as a Major Site of CD4 <sup>+</sup> T Cell Depletion and Viral Replication in SIV Infection

Ronald S. Veazey, MaryAnn DeMaria, Laura V. Chalifoux et al. · Science · 1998 · 1.4K citations

, , +13

Primary HIV-1 Infection Is Associated with Preferential Depletion of CD4+ T Lymphocytes from Effector Sites in the Gastrointestinal Tract

Saurabh Mehandru, Michael A. Poles, Klara Tenner‐Racz et al. · The Journal of Experimental Medicine · 2004 · 1.1K citations · Full text

, , +17

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

James Arthos, Claudia Cicala, Elena Martinelli et al. · Nature Immunology · 2008 · 552 citations

, , +17