Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.3K citations · Full text

Replicative Senescence, Developmental Biology, Aging +14

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Shankar Srinivas, Tomoko Watanabe, Chyuan‐Sheng Lin et al. · BMC Developmental Biology · 2001 · 3.1K citations · Full text

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Defining the Epithelial Stem Cell Niche in Skin

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Label-retaining Cells, Skin Stem Cell, Dermatology +20

A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

Jason Moffat, Dorre A. Grueneberg, Xiaoping Yang et al. · Cell · 2006 · 1.8K citations · Full text

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p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

Andreas Villunger, Ewa M. Michalak, Leigh Coultas et al. · Science · 2003 · 1.3K citations