Ibogaine possesses a selective affinity for σ2 receptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Rat liver and kidney contain high densities of σ1 and σ2 receptors: characterization by ligand binding and photoaffinity labeling

Susan B. Hellewell, Ashley Bruce, Glen I. Feinstein et al. · European Journal of Pharmacology Molecular Pharmacology · 1994 · 437 citations

Medicine, Biochemistry, Pharmacology +12

Degeneration of purkinje cells in parasagittal zones of the cerebellar vermis after treatment with ibogaine or harmaline

Elizabeth O’Hearn, M.E. Molliver · Neuroscience · 1993 · 220 citations

Life Sciences, Neurobiology, Neuroscience +16

Effects and aftereffects of ibogaine on morphine self-administration in rats

S.D. Glick, Kent L. Rossman, S. Steindorf et al. · European Journal of Pharmacology · 1991 · 195 citations

Medicine, Pharmacology, Behavioral Pharmacology +10

Autoradiographic visualization of haloperidol-sensitive sigma receptors in guinea-pig brain

Stafford McLean, E Weber · Neuroscience · 1988 · 177 citations

Medicine, Neuroscience, Pharmacology +7