Concepedia

Activation of p53 with Nutlin-3a radiosensitizes lung cancer cells via enhancing radiation-induced premature senescence

Hongmei Luo, C Yount, Hainan Lang, Aimin Yang, Ellen C. Riemer, Katherine Lyons, Kenneth N. Vanek, Gerard A. Silvestri, Bradley A. Schulte, Gavin Y. Wang

Lung Cancer · 2013 · 66 citations · 32 references

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32

Cancer Statistics, 2009

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2009 · 9.7K citations · Full text

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

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In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

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Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Wen Xue, Lars Zender, Cornelius Miething et al. · Nature · 2007 · 2.4K citations

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