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Osthole improves an accelerated focal segmental glomerulosclerosis model in the early stage by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated COX-2 expression and apoptosis

Renal PathologyImmunologyRenal InflammationCell DeathOxidative StressInflammationGlomerulonephritisNf-κb-mediated Cox-2 ExpressionNrf2 Antioxidant PathwayMetabolic SignalingChronic Kidney DiseaseCell SignalingEarly StageMolecular SignalingVascular BiologyRenal PathophysiologyReactive Oxygen SpeciePharmacologyMedicineNephrology