Lipase-promoted kinetic resolution of racemic, P-chiral hydroxymethylphosphonates and phosphinates

New hybrid transition state analog inhibitors of HIV protease with peripheric C2-symmetry

Bernd Stowasser, Karl‐Heinz Budt, Jianqi Li et al. · Tetrahedron Letters · 1992 · 407 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Preparation of peptidic α-hydroxy phosphonates a new class of transition state analog renin inhibitors

Dinesh V. Patel, Katherine Rielly-Gauvin, Denis E. Ryono · Tetrahedron Letters · 1990 · 237 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Enantiopreference of Lipase from Pseudomonas cepacia toward Primary Alcohols

Alexandra N. E. Weissfloch, Romas J. Kazlauskas · The Journal of Organic Chemistry · 1995 · 166 citations

Life Sciences, Biochemistry, Microbiology +9

Enzymes in organic chemistry, part 1: Enantioselective hydrolysis of α-(acyloxy)phosphonates by esterolytic enzymes

Yongfu Li, Friedrich Hammerschmidt · Tetrahedron Asymmetry · 1993 · 94 citations

Life Sciences, Biochemistry, Chemistry +16

Retention stereochemistry in a Grignard displacement reaction at chiral phosphorus. Absolute configuration of O-menthyl S-methyl phenylphosphonothiolate

Kurt Mislow, Jerry Donohue, N. Mandel et al. · Journal of the American Chemical Society · 1971 · 40 citations

Natural Sciences, Chemistry, Inorganic Chemistry +8