α2-Adrenergic agonist modulation of [35S]GTPγS binding to guanine-nucleotide-binding-proteins in human platelet membranes

A simple and sensitive saturation assay method for the measurement of adenosine 3′:5′-cyclic monophosphate

B. L. Brown, J. D. M. Albano, Roger Ekins et al. · Biochemical Journal · 1971 · 1.5K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.

Philippe Samama, Susanna Cotecchia, Tommaso Costa et al. · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium.

Debra A. Horstman, Suzanne Brandon, Amy L. Wilson et al. · Journal of Biological Chemistry · 1990 · 273 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.

Jinmin Zhu, Lei Luo, J G Li et al. · PubMed · 1997 · 164 citations

Life Sciences, Cell Biology, Pharmacology +17

Measurement of guanine nucleotide-binding protein activation by A1 adenosine receptor agonists in bovine brain membranes: stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding.

A. Lorenzen, M Fuss, Heidrun Vogt et al. · Molecular Pharmacology · 1993 · 162 citations

Life Sciences, Biochemistry, Pharmacology +14