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Synthesis of a novel duocarmycin derivative DU-257 and its application to immunoconjugate using poly(ethylene glycol)-dipeptidyl linker capable of tumor specific activation

Tumor Specific ActivationMedicinal ChemistryEthylene GlycolBioorganic ChemistryPolymer-drug ConjugateNatural SciencesMedicineBioconjugationAnti-cancer AgentPharmacology-Dipeptidyl LinkerBiomolecular EngineeringDrug Discovery