A mouse model of autosomal recessive polycystic kidney disease with biliary duct and proximal tubule dilatation

The Polycystic Kidney Disease Proteins, Polycystin-1, Polycystin-2, Polaris, and Cystin, Are Co-Localized in Renal Cilia

Bradley K. Yoder, Xiaoying Hou, Lisa M. Guay‐Woodford · Journal of the American Society of Nephrology · 2002 · 939 citations

Medicine, Cell Biology, Molecular Biology +16

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

Christopher J. Ward, Marie C. Hogan, Sandro Rossetti et al. · Nature Genetics · 2002 · 763 citations

Medicine, Genetics, Molecular Genetics +14

Regression of human metastatic renal cell carcinoma after vaccination with tumor cell–dendritic cell hybrids

A. Kugler, Gernot Stuhler, Peter Walden et al. · Nature Medicine · 2000 · 646 citations

Medicine, Immunology, Oncology +12

FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left–right determination

Yosuke Tanaka, Yasushi Okada, Nobutaka Hirokawa · Nature · 2005 · 528 citations

Life Sciences, Cell Biology, Developmental Biology +14

PKHD1, the Polycystic Kidney and Hepatic Disease 1 Gene, Encodes a Novel Large Protein Containing Multiple Immunoglobulin-Like Plexin-Transcription–Factor Domains and Parallel Beta-Helix 1 Repeats

Luiz F. Onuchic, Laszlo Furu, Yasuyuki Nagasawa et al. · The American Journal of Human Genetics · 2002 · 510 citations · Full text

Medicine, Genetics, Molecular Genetics +8