Increased Bone Formation in Mice Lacking Apolipoprotein E - Concepedia

Concepedia

Publication | Closed Access

Increased Bone Formation in Mice Lacking Apolipoprotein E

100

Citations

46

References

2005

Year

Arndt F. Schilling, Thorsten Schinke, Christian Münch, Matthias Gebauer, Andreas Niemeier, Matthias Priemel, Thomas Streichert, Johannes M. Rueger, Michael Amling

Journal of Bone and Mineral Research

Abstract

The specific induction of ApoE gene expression during osteoblast differentiation along with the increased bone formation rate observed in ApoE-deficient mice shows that ApoE has a physiologic role as a regulator of osteoblast function.

References

	Year	Citations
Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter, Science	1993	9.3K
Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee A. M. Parfitt, Marc K. Drezner, Francis H. Glorieux, Journal of Bone and Mineral Research SurgeryChairman BoneAnatomyOsteoporosisOrthopaedic Surgery	1987	5K
Bone Histomorphometry : Standardization of Nomenclature, Symbols, and Units A. M. Parfitt, M. K. Drezner, Francis H. Glorieux, Journal of Bone and Mineral Research Bone ImagingBone HistomorphometryAnatomyBone DensityMedicine	1987	3.3K
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells Andrew Plump, Jonathan D. Smith, Tony Hayek, Cell Metabolic SyndromeLipid DisorderOxysterolGeneticsHyperlipidemia	1992	2.2K
LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development Yaoqin Gong, Roger B. Slee, N Fukai, Cell Bone AccrualSclerostinSignal TransductionMolecular PhysiologyDevelopmental Biology	2001	2.2K
Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E Sunny H. Zhang, Robert L. Reddick, Jorge A. Piedrahita, Science Vascular DiseasePathologyHyperlipidemiaOxidative StressInflammation	1992	2.2K
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein Guangbin Luo, Patricia Ducy, Marc D. McKee, Nature MechanobiologyMedicinePhysiologyMatrix Gla ProteinTissue Physiology	1997	2.1K
Leptin Inhibits Bone Formation through a Hypothalamic Relay Patricia Ducy, Michael Amling, Shu Takeda, Cell SclerostinPhysiologyHypothalamic PeptideHypothalamic RelayNervous System	2000	2.1K
Increased bone formation in osteocalcin-deficient mice Patricia Ducy, Christelle Desbois, Brendan F. Boyce, Nature Orthopaedic SurgeryOsteoarthritisOsteogenesisBone HomeostasisBone Formation	1996	1.7K
Leptin Regulates Bone Formation via the Sympathetic Nervous System Shu Takeda, Florent Elefteriou, Régis Levasseur, Cell SclerostinSympathetic Nervous SystemPhysiologyHypothalamic PeptideCentral Nervous System	2002	1.7K

Page 1