Geranylgeraniol – A new potential therapeutic approach to bisphosphonate associated osteonecrosis of the jaw

References

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	Year	Citations
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation <i>in vitro</i> John Fisher, Michael J. Rogers, J. M. Halasy, Proceedings of the National Academy of Sciences SclerostinBone ResorptionMacrophage ApoptosisAlendronate MechanismOsteoporosis	1999	679
Farnesol and Geranylgeraniol Prevent Activation of Caspases by Aminobisphosphonates: Biochemical Evidence for Two Distinct Pharmacological Classes of Bisphosphonate Drugs Helena L. Benford, Julie C. Frith, Seppo Auriola, Molecular Pharmacology	1999	256
The Role of Geranylgeranylation in Bone Resorption and Its Suppression by Bisphosphonates in Fetal Bone Explants In Vitro: A Clue to the Mechanism of Action of Nitrogen-Containing Bisphosphonates Ermond van Beek, Clemens W.G.M. Löwik, Gabri van der Pluijm, Journal of Bone and Mineral Research	1999	240
The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway. C M Shipman, Peter I. Croucher, R.G.G. Russell, PubMed Chemoprevention StrategyApoptosisImmunologyCell DeathPharmacotherapy	1998	220
“Bis-phossy jaws” – High and low risk factors for bisphosphonate-induced osteonecrosis of the jaw Mario Hakim Abu-Id, Patrick H. Warnke, Joachim Gottschalk, Journal of Cranio-Maxillofacial Surgery Bone DiseaseBone HealthOral BiologyBone MetabolismLow Risk Factors	2008	217
Updated recommendations for managing the care of patients receiving oral bisphosphonate therapy Beatrice J. Edwards, John W. Hellstein, Peter L. Jacobsen, The Journal of the American Dental Association Treatment OptionOutcomes ResearchOral MedicinePediatric DysphoniaMedicine	2008	187
Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway. SS Virtanen, H. Kalervo Väänänen, Pirkko Härkönen, PubMed SclerostinCancer BiologyOsteoporosisTumor BiologyAlendronate Inhibits Invasion	2002	163
Hyperbaric Oxygen Treatment and Bisphosphonate-Induced Osteonecrosis of the Jaw: A Case Series John J. Freiberger, Rebecca Padilla-Burgos, Austin Chhoeu, Journal of Oral and Maxillofacial Surgery Bone DiseaseMedicineDistraction OsteogenesisBone MetabolismHyperbaric Oxygen Treatment	2007	156
New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects Christophe Denoyelle, J. P. Vannier, Jeannette Soria, British Journal of Cancer	2003	155
Influence of bisphosphonates on endothelial cells, fibroblasts, and osteogenic cells Christian Walter, Marc Klein, Andreas Pabst, Clinical Oral Investigations MechanobiologyEndothelial CellsBone Morphogenic ProteinMedicinePhysiology	2009	148

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