R.G.G. Russell

Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras

Steven P. Luckman, D. E. Hughes, Fraser P. Coxon et al. · Journal of Bone and Mineral Research · 1998 · 1.2K citations · Full text

Sclerostin, Mevastatin-induced Apoptosis, Molecular Regulation +25

An interleukin 1 like factor stimulates bone resorption in vitro

Maxine Gowen, David D. Wood, Earl J. Ihrie et al. · Nature · 1983 · 1K citations

Inflammation, Bone Morphogenic Protein, Immunology +10

Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite

George H. Nancollas, Ruikang Tang, Roger Phipps et al. · Bone · 2005 · 852 citations

Bone Disease, Bone Health, Hydroxyapatite +7

Diphosphonates Inhibit Hydroxyapatite Dissolution in vitro and Bone Resorption in Tissue Culture and in vivo

H. Fleisch, R. Graham, R.G.G. Russell et al. · Science · 1969 · 758 citations

Bone Disease, Bone Health, Bone Resorption +13

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation <i>in vitro</i>

John Fisher, Michael J. Rogers, J. M. Halasy et al. · Proceedings of the National Academy of Sciences · 1999 · 679 citations

Sclerostin, Bone Resorption, Macrophage Apoptosis +17