Concepedia

Identification of novel mammalian squalene synthase inhibitors using a three-Dimensional pharmacophore

Ian J. S. Fairlamb, Julia M. Dickinson, Rachael O’Connor, Séamus P.J. Higson, Lynsey Grieveson, V. Marin

Bioorganic & Medicinal Chemistry · 2002 · 19 citations · 28 references

DOI

Concepts

References

28

Stereo-controlled synthesis of dl-prostaglandins F2.alpha. and E2

E. J. Corey, Ned M. Weinshenker, Thomas Schaaf et al. · Journal of the American Chemical Society · 1969 · 572 citations

, , +16

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase.

James D. Bergstrom, Marc M. Kurtz, Deborah J. Rew et al. · Proceedings of the National Academy of Sciences · 1993 · 335 citations

, , +12

The ensemble approach to distance geometry: application to the nicotinic pharmacophore

Robert P. Sheridan, Ramaswamy Nilakantan, Jonathan S. Dixon · Journal of Medicinal Chemistry · 1986 · 249 citations

, , +16

Crystal Structure of Human Squalene Synthase

Jayvardhan Pandit, Dennis E. Danley, Gayle K. Schulte et al. · Journal of Biological Chemistry · 2000 · 237 citations · Full text

, , +17

Total Synthesis of Prostaglandins F<sub>2α</sub> and E<sub>2</sub> as the Naturally Occuring Forms

E. J. Corey, Thomas Schaaf, W. Frederick Huber et al. · Journal of the American Chemical Society · 1970 · 220 citations

, , +9