Non-imidazole histamine H3 receptor ligands incorporating antiepileptic moieties

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

On the medicinal chemistry of ferrocene

M.F.R. Fouda, Mokhles M. Abd‐Elzaher, Rafeek A. Abdelsamaia et al. · Applied Organometallic Chemistry · 2007 · 458 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

BF2.649 [1-{3-[3-(4-Chlorophenyl)propoxy]propyl}piperidine, Hydrochloride], a Nonimidazole Inverse Agonist/Antagonist at the Human Histamine H3 Receptor: Preclinical Pharmacology

Xavier Ligneau, David Perrin, Laurent Landais et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 234 citations

Medicine, Neuroscience, Pharmacology +10

The Evaluation and Treatment of Seizures

Mark L. Scheuer, Timothy A. Pedley · New England Journal of Medicine · 1990 · 136 citations

Medicine, Neurology, Pharmacotherapy +10

Influence of imidazole replacement in different structural classes of histamine H3-receptor antagonists

Galina Meier, Joachim Apelt, Ulrich Reichert et al. · European Journal of Pharmaceutical Sciences · 2001 · 108 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15