Concepedia

Novel Small Molecule Inhibitors of Caspase-3 Block Cellular and Biochemical Features of Apoptosis

Clay W. Scott, Cindy Sobotka-Briner, Deidre Wilkins, Robert T. Jacobs, James J. Folmer, William J. Frazee, Ratan V. Bhat, Smita V. Ghanekar, David Aharony

Journal of Pharmacology and Experimental Therapeutics · 2003 · 61 citations · 26 references

DOI

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References

26

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

Keisuke Kuida, Timothy S. Zheng, Songqing Na et al. · Nature · 1996 · 1.9K citations

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Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors

Margarita García‐Calvo, Erin P. Peterson, Barbara Leiting et al. · Journal of Biological Chemistry · 1998 · 987 citations · Full text

, , +17

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

Minna Woo, Razqallah Hakem, Marı́a S. Soengas et al. · Genes & Development · 1998 · 842 citations · Full text

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Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

François G. Gervais, Daigen Xu, George S. Robertson et al. · Cell · 1999 · 785 citations · Full text

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Activation of CPP32-Like Caspases Contributes to Neuronal Apoptosis and Neurological Dysfunction after Traumatic Brain Injury

Alexander G. Yakovlev, Susan M. Knoblach, Lei Fan et al. · Journal of Neuroscience · 1997 · 583 citations · Full text

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