A Stable, Multi-Subunit Complex of β2Glycoprotein I

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

H. Patrick McNeil, Richard J. Simpson, C.N. Chesterman et al. · Proceedings of the National Academy of Sciences · 1990 · 1.6K citations

Pharmacy, Biochemistry, Chromatographic Analysis +15

Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor

Mónica Galli, Tiziano Barbui, Paul Comfurius et al. · The Lancet · 1990 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.

Eiji Matsuura, Yoshiko Igarashi, Tatsuji Yasuda et al. · The Journal of Experimental Medicine · 1994 · 531 citations · Full text

Medicine, Biochemistry, Protein-protein Interactions +13

Pregnancy Loss in the Antiphospholipid-Antibody Syndrome — A Possible Thrombogenic Mechanism

Jacob H. Rand, Xiao-Xuan Wu, Harry A.M. Andree et al. · New England Journal of Medicine · 1997 · 528 citations · Full text

Medicine, Immunology, Obstetrics +17

beta 2-Glycoprotein I: a plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway

Inger Schousboe · Blood · 1985 · 363 citations · Full text

Medicine, Biochemistry, Pharmacology +15