Concepedia

Identification of N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4

Qian Zhao, Liying Ma, Shibo Jiang, Hong Lü, Shuwen Liu, Yuxian He, N. Strick, Nouri Neamati, Asim K. Debnath

Virology · 2005 · 215 citations · 44 references

DOI

Concepts

References

44

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

Peter D. Kwong, Richard T. Wyatt, James E. Robinson et al. · Nature · 1998 · 3K citations · Full text

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Core Structure of gp41 from the HIV Envelope Glycoprotein

David C. Chan, Deborah Fass, James M. Berger et al. · Cell · 1997 · 1.9K citations · Full text

, , +13

The antigenic structure of the HIV gp120 envelope glycoprotein

Richard T. Wyatt, Peter D. Kwong, Elizabeth Desjardins et al. · Nature · 1998 · 1.2K citations · Full text

, , +9

Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding.

Quentin J. Sattentau, John P. Moore · The Journal of Experimental Medicine · 1991 · 598 citations · Full text

, , +15

Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion

Grigory B. Melikyan, Ruben M. Markosyan, Hila Hemmati et al. · The Journal of Cell Biology · 2000 · 584 citations · Full text

, , +16