Journal of the Chemical Society Chemical Communications · 1972 · 19 citations · 0 references
Natural SciencesBiochemistryChemistryEnzyme MechanismNatural Product BiosynthesisOrganic SynthesisHydrogen Atom TransferProtoporphyrin Ix MetabolismProtoporphyrin MetabolismStereospecific Reactions
Coproporphyrinogen-III (1) is shown to be converted biochemically into protoporphyrin-IX (4) with loss of one hydrogen atom from each propionate residue on rings A and B and the 3H-tracer results are consistent with a stereospecific process.