2008 · 30 citations · 15 references
Life SciencesBiostatisticsGenomic Data AnalysisPhylogeneticsSequence AnalysisPairwise AlignmentSequence AlignmentOptimal AlignmentPairwise Alignment ScoringPermutationsSequence Alignment ScoringSequence SimilaritySequence Similarity ScoringStatistical Significance Of AlignmentsStatistical Significance Testing
Pairwise sequence alignment methods are now often used when analyzing eyetracking data [Hacisalihzade et al. 1992; Brandt and Stark 1997; Josephson and Holmes 2002, 2006; Pan et al. 2004; Heminghous and Duchowski 2006]. While optimal sequence alignment scores provide a valuation of similarity and difference, they do not readily provide a statistical test of similarity or difference. Furthermore, pairwise alignment scores cannot be used to compare groups of scan patterns directly. Using a statistic that compiles these pairwise alignment scores, a statistical evaluation of similarity can be made by repeatedly computing scores from different permutations of scan pattern groupings. This test produces a p-value as a level of statistical significance.
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