Modulation of rat brain insulin receptor kinase activity in diabetes

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

George Scatchard · Annals of the New York Academy of Sciences · 1949 · 19.9K citations

Protein Chemistry, Protein Function, Protein Assembly +5

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

Leland Ellis, Éric Clauser, David O. Morgan et al. · Cell · 1986 · 1.1K citations

Signal Transduction, Biochemistry, G Protein-coupled Receptor +9

Identification of insulin in rat brain.

Jana Havránková, D. E. Schmechel, Jesse Roth et al. · Proceedings of the National Academy of Sciences · 1978 · 604 citations · Full text

Brain Insulin, Insulin Signaling, Social Sciences +19

Acute insulin action requires insulin receptor kinase activity: introduction of an inhibitory monoclonal antibody into mammalian cells blocks the rapid effects of insulin.

David O. Morgan, Richard A. Roth · Proceedings of the National Academy of Sciences · 1987 · 222 citations · Full text

Immunology, Insulin Receptor, Insulin Signaling +20

Insulin receptor signaling. Activation of multiple serine kinases.

M P Czech, Jes K. Klarlund, K A Yagaloff et al. · Journal of Biological Chemistry · 1988 · 197 citations · Full text

Insulin Receptor, Insulin Signaling, Metabolic Syndrome +21