Concepedia

Pharmacokinetic/Pharmacodynamic modeling of abexinostat-induced thrombocytopenia across different patient populations: application for the determination of the maximum tolerated doses in both lymphoma and solid tumour patients

Quentin Chalret du Rieu, Sylvain Fouliard, Mélanie White‐Koning, Ioana Kloos, Étienne Chatelut, Marylore Chenel

Investigational New Drugs · 2014 · 14 citations · 31 references

DOI

Concepts

References

31

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations

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Design and Analysis of Phase I Clinical Trials

Barry E. Storer · Biometrics · 1989 · 932 citations

, , +9

Accelerated Titration Designs for Phase I Clinical Trials in Oncology

Richard Simon, Larry Rubinstein, Susan G. Arbuck et al. · JNCI Journal of the National Cancer Institute · 1997 · 640 citations · Full text

, , +17

Evaluation of methods for estimating population pharmacokinetic parameters. I. Michaelis-menten model: Routine clinical pharmacokinetic data

Lewis B. Sheiner, Stuart L. Beal · Journal of Pharmacokinetics and Biopharmaceutics · 1980 · 556 citations

, , +12

The Quantitative Relation between Platelet Count and Hemorrhage in Patients with Acute Leukemia

Lawrence A. Gaydos, Emil J. Freireich, Nathan Mantel · New England Journal of Medicine · 1962 · 534 citations

, , +13