Digenic parkinsonism: Investigation of the synergistic effects of PRKN and LRRK2

Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

Alexander Zimprich, Saskia Biskup, Petra Leitner et al. · Neuron · 2004 · 3K citations · Full text

Mendelian Disorder, Genetic Disorder, Parkinson Disease +5

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

Andrew B. West, Darren J. Moore, Saskia Biskup et al. · Proceedings of the National Academy of Sciences · 2005 · 1.2K citations · Full text

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

Benoit I. Giasson, Mark S. Forman, Makoto Higuchi et al. · Science · 2003 · 869 citations

Identification of a Novel LRRK2 Mutation Linked to Autosomal Dominant Parkinsonism: Evidence of a Common Founder across European Populations

Jennifer M. Kachergus, Ignácio F. Mata, Mary Hulihan et al. · The American Journal of Human Genetics · 2005 · 534 citations · Full text

Molecular Neuroscience, Mendelian Disorder, Genetic Disorder +7

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

Christian Johannes Gloeckner, Norbert Kinkl, Annette Schumacher et al. · Human Molecular Genetics · 2005 · 474 citations · Full text