3-Acetyl-5-acylpyridin-2(1H)-ones and 3-acetyl-7,8-dihydro-2,5(1H,6H)-quinolinediones: synthesis, cardiotonic activity and computational studies

Cardiotonic Activity of Milrinone, a New and Potent Cardiac Bipyridine, on the Normal and Failing Heart of Experimental Animals

Adawia A. Alousi, Jay M. Canter, Maria J. Montenaro et al. · Journal of Cardiovascular Pharmacology · 1983 · 219 citations

Medicine, Cardiology, Canine Internal Medicine +16

Cardiotonic agents. 8. Selective inhibitors of adenosine 3',5'-cyclic phosphate phosphodiesterase III. Elaboration of a five-point model for positive inotropic activity

Walter H. Moos, Christine Humblet, Ila Sircar et al. · Journal of Medicinal Chemistry · 1987 · 84 citations · Full text

Medicine, Cardiology, Pharmacology +12

Reaction of 2‐dimethylaminomethylene‐1,3‐diones with dinucleophiles. I. Synthesis of 1,5‐disubstituted 4‐acylpyrazoles

P. SCHENONE, Luisa Mosti, Giulia Menozzi · Journal of Heterocyclic Chemistry · 1982 · 79 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +9

A pharmacological, crystallographic, and quantum chemical study of new inotropic agents

P. Dorigo, R.M. Gaion, P. Belluco et al. · Journal of Medicinal Chemistry · 1993 · 40 citations

Natural Sciences, Chemistry, Pharmacology +8

Cardiotonic agents. 3. A topographical model of the cardiac cAMP phosphodiesterase receptor.

Paul Erhardt, Alfred A. Hagedorn, Michael Sabio · Molecular Pharmacology · 1988 · 40 citations

Medicine, Medicinal Chemistry, Pharmacology +17