Concepedia

Detection of antibodies against therapeutic proteins in the presence of residual therapeutic protein using a solid-phase extraction with acid dissociation (SPEAD) sample treatment prior to ELISA

Holly W. Smith, Anthony Butterfield, Deqin Sun

Regulatory Toxicology and Pharmacology · 2007 · 130 citations · 10 references

DOI

Concepts

References

10

Antibodies, a laboratory manual

Biomedicine & Pharmacotherapy · 1989 · 12.5K citations

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Influence of Immunogenicity on the Long-Term Efficacy of Infliximab in Crohn's Disease

Filip Baert, Maja Noman, Séverine Vermeire et al. · New England Journal of Medicine · 2003 · 2K citations · Full text

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Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products

Anthony R. Mire‐Sluis, Yu Chen Barrett, Viswanath Devanarayan et al. · Journal of Immunological Methods · 2004 · 621 citations

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An acid dissociation bridging ELISA for detection of antibodies directed against therapeutic proteins in the presence of antigen

Aaron K. Patton, Michael C. Mullenix, Steven J. Swanson et al. · Journal of Immunological Methods · 2005 · 201 citations

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Monoclonal antibodies, immunogenicity, and associated infusion reactions.

Adam S. Cheifetz, Lloyd Mayer · PubMed · 2005 · 152 citations

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