Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract ofScutellaria baicalensis, PF-2405 in rats

Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi

Zhonghong Gao, Xiangliang Yang, Huibi Xu · Biochimica et Biophysica Acta (BBA) - General Subjects · 1999 · 611 citations

Life Sciences, Botany, Plant Sciences +14

Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin.

Den‐En Shieh, Li‐Teh Liu, C.C. Lin · PubMed · 2000 · 343 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines

Shinichi Ikemoto, Kazunobu Sugimura, Naomasa Yoshida et al. · Urology · 2000 · 285 citations

Medicine, Oncology, Pharmacology +8

Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide11Abbreviations: NO, nitric oxide; iNOS, inducible nitricoxide synthase; COX-2, cyclooxygenase-2; PGE2,prostaglandin E2; MTT,3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide, LPS,lipopolysaccharide; NLA, N-nitro-l-arginine; andL-NAME, N-nitro-l-arginine methyl ester.

Yen‐Chou Chen, Shing‐Chuan Shen, Lih-Geeng Chen et al. · Biochemical Pharmacology · 2001 · 270 citations

Life Sciences, Biochemistry, Pharmacology +12

Balicalin, the Predominant Flavone Glucuronide of Scutellariae Radix, is Absorbed from the Rat Gastrointestinal Tract as the Aglycone and Restored to its Original Form

Teruaki Akao, Kiyoshi Kawabata, Erika Yanagisawa et al. · Journal of Pharmacy and Pharmacology · 2000 · 249 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12