Journal of Wound Ostomy and Continence Nursing · 2011 · 248 citations · 31 references
MedicineDermatologyPathologyDermatopathologyHypersensitivityPodiatric DermatologyContact DermatitisMoisture DamageSkin Barrier FunctionSkin InfectionsSkin IrritationTissue DamageDermal InjuryDermal IrritantsMoistureMoisture-related LesionsPeristomal Irritant DermatitisPeristomal Skin BreakdownSkin DrynessSkin Moisturization
Moisture-associated skin damage (MASD) is caused by prolonged exposure to various sources of moisture, including urine or stool, perspiration, wound exudate, mucus, saliva, and their contents. MASD is characterized by inflammation of the skin, occurring with or without erosion or secondary cutaneous infection. Multiple conditions may result in MASD; 4 of the most common forms are incontinence-associated dermatitis, intertriginous dermatitis, periwound moisture-associated dermatitis, and peristomal moisture-associated dermatitis. Although evidence is lacking, clinical experience suggests that MASD requires more than moisture alone. Instead, skin damage is attributable to multiple factors, including chemical irritants within the moisture source, its pH, mechanical factors such as friction, and associated microorganisms. To prevent MASD, clinicians need to be vigilant both in maintaining optimal skin conditions and in diagnosing and treating minor cases of MASD prior to progression and skin breakdown.
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Stratum corneum lipids: the effect of ageing and the seasons
Julia S. Rogers, Clive R. Harding, Abigail K. Mayo et al. · Archives of Dermatological Research · 1996 · 411 citations
Filaggrin in atopic dermatitis
Gráinne M. O’Regan, Aileen Sandilands, W.H. Irwin McLean et al. · Journal of Allergy and Clinical Immunology · 2008 · 347 citations
Medicine, Dermatology, Immunology +12