The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine

Experimental pathology of the liver

Gm. Higgins · Medical Entomology and Zoology · 1931 · 3.1K citations

Medicine, Pathobiology, Pathology +12

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

A. Loveless · Nature · 1969 · 948 citations

Pharmacy, Pharmacology, Toxicology +14

FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES

PD LAWLEY, P. Brookes · Biochemical Journal · 1963 · 799 citations · Full text

Pharmacy, Biochemistry, Chemistry +9

Methylation of deoxyribonucleic acid in cultured mammalian cells by <i>N</i>-methyl-<i>N</i>′-nitro-<i>N</i>-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

P.D. Lawley, Carolyn J. Thatcher · Biochemical Journal · 1970 · 495 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine <i>in vivo</i>

PN MAGEE, Emmanuel Farber · Biochemical Journal · 1962 · 398 citations · Full text

Pharmacy, Molecular Biology, Toxicology +11