Targeted cleavage of HIV-1 coreceptor-CXCR-4 by RNA-cleaving DNA-enzyme: inhibition of coreceptor function

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

Rong Liu, William A. Paxton, Sunny Choe et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Infectious Diseases +13

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Michel Samson, Frédérick Libert, Benjamin J. Doranz et al. · Nature · 1996 · 2.9K citations

Life Sciences, Genetics, Molecular Genetics +11

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the <i>CKR5</i> Structural Gene

Michael Dean, Mary Carrington, Cheryl A. Winkler et al. · Science · 1996 · 2.5K citations

Life Sciences, Genetics, Molecular Genetics +8

A general purpose RNA-cleaving DNA enzyme

Stephen W. Santoro, Gerald F. Joyce · Proceedings of the National Academy of Sciences · 1997 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +16

The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

Yaoxing Huang, William A. Paxton, Steven M. Wolinsky et al. · Nature Medicine · 1996 · 1.4K citations

Life Sciences, Genetics, Infectious Diseases +13