Development and application of a radioimmunoassay for methotrexate

Methotrexate: Distribution in Cerebrospinal Fluid after Intravenous, Ventricular and Lumbar Injections

William R. Shapiro, Dean F. Young, Bipin M. Mehta · New England Journal of Medicine · 1975 · 684 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Methotrexate Pharmacokinetics

Kenneth B. Bischoff, Robert L. Dedrick, Daniel S. Zaharko et al. · Journal of Pharmaceutical Sciences · 1971 · 479 citations · Full text

Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase

William C. Werkheiser · Journal of Biological Chemistry · 1961 · 385 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +14

7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate.

Samuel A. Jacobs, Ronald G. Stoller, Bruce A. Chabner et al. · Journal of Clinical Investigation · 1976 · 256 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

New Approaches to Cancer Chemotherapy with Methotrexate

Howard L. Bleich, Emily S. Boro, E Frei et al. · New England Journal of Medicine · 1975 · 232 citations

Medicine, Oncology, Pharmacology +16