Publication | Closed Access
nBu4NI-Catalyzed oxidative imidation of ketones with imides: synthesis of α-amino ketones
105
Citations
35
References
2014
Year
EngineeringBiochemistryReactive Nitrogen Specieα-Amino KetonesNatural SciencesDiversity-oriented SynthesisOrganic ChemistryNbu4ni-catalyzed Oxidative ImidationCatalysisNatural Product SynthesisSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringAvailable Phthalimide
nBu4NI-Catalyzed oxidative imidation of ketones and imides for the synthesis of α-amino ketones were realized for the first time. The methodology is characterized by its wide substrate scope even for acetone with readily available phthalimide, saccharin and succinimide, which opens a new pathway for direct imidation of ketones.
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