Chemical Communications · 2014 · 106 citations · 35 references
Natural SciencesBiochemistryChemistryCatalysisAmino Acid ChemistryKetonesSubstrate Scope
nBu4NI-Catalyzed oxidative imidation of ketones and imides for the synthesis of α-amino ketones were realized for the first time. The methodology is characterized by its wide substrate scope even for acetone with readily available phthalimide, saccharin and succinimide, which opens a new pathway for direct imidation of ketones.
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