Palladium-Catalyzed C−H Aminations of Anilides with <i>N</i>-Fluorobenzenesulfonimide

Abstract

The first amide-directed, palladium-catalyzed, intermolecular, highly selective C-H aminations with the non-nitrene-based nitrogen source N-fluorobenzenesulfonimide have been developed. This methodology might provide a new pathway for directed metal-catalyzed aromatic C-H amination.