Enhancement by hydroxyurea of the anti-human immunodeficiency virus type 1 potency of 2′-β-fluoro-2′,3′-dideoxyadenosine in peripheral blood mononuclear cells

Hydroxyurea as an Inhibitor of Human Immunodeficiency Virus-Type 1 Replication

Franco Lori, Andrei Malykh, Andrea Cara et al. · Science · 1994 · 321 citations

Life Sciences, Biochemistry, Molecular Biology +16

Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs

Staffan Eriksson, Borys Kierdaszuk, Birgitte Munch‐Petersen et al. · Biochemical and Biophysical Research Communications · 1991 · 238 citations

Life Sciences, Molecular Biology, Nucleic Acid Biochemistry +6

Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis.

Vera Bianchi, E Pontis, Peter Reichard · Journal of Biological Chemistry · 1986 · 221 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV

Víctor E. Márquez, Christopher K. H. Tseng, Hiroaki Mitsuya et al. · Journal of Medicinal Chemistry · 1990 · 211 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study.

T Shirasaka, Robert Yarchoan, Maggie O’Brien et al. · Proceedings of the National Academy of Sciences · 1993 · 132 citations

Medicine, Infectious Diseases, Pharmacology +13