Novel DMARDs on the basis of a new concept of dual cytokine regulation, TNF-α suppression and IL-10 augmentation

Quantitative mechanistic studies in simultaneous fluid flow and intestinal absorption using steroids as model solutes

Ichiro Komiya, J.Y. Park, A. Kamani et al. · International Journal of Pharmaceutics · 1980 · 228 citations · Full text

Pharmacy, Pharmacokinetics, Physiology +17

Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints

Fionula M. Brennan, Deena L. Gibbons, Andrew P. Cope et al. · European Journal of Immunology · 1992 · 91 citations

Life Sciences, Immunology, Pathobiology +12

Novel phenylpiperazine derivatives as dual cytokine regulators with TNF-α suppressing and IL-10 augmenting activity

Tokushi Hanano, Kunitomo Adachi, Yoshiyuki Aoki et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 14 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Inhibitory effects of anti-inflammatory drugs on type II collagen induced arthritis in rats.

Keiko Yamaki, Hideo NAKAGAWA, Susumu Tsurufuji · Annals of the Rheumatic Diseases · 1987 · 12 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +15